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Ningbo J&S Botanics Inc.
[China]
Address:
529 Yuanbaoshan Road Beilun District, Ningbo Zhejiang 315806 China
Phone:
86-0574-27855880
Contact name:
Andy Lee
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Ningbo J&S Botanics Inc.



 
Food Additives

Levodopa

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Levodopa

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Plant Source: vicia faba leaf, Mucuna cochin - chinensis (Lour) A. Cheval. Seed.


Discribtion:
The gold standard of present therapy is the drug levodopa (also called L-dopa). L-Dopa (from the full name L-3, 4-dihydroxyphenylalanine) is a neutral amino acid found naturally in plants and animals. After oral ingestion, it is absorbed in the small intestine. Absorption can be delayed by meals and increased gastric acidity. Absorbed levodopa is not bound to plasma protein. Nerve cells can use levodopa to make dopamine and replenish the brain's dwindling supply. Dopamine cannot be given directly because it doesn't cross the blood-brain barrier, the elaborate meshwork of fine blood vessels and cells that filters blood reaching the brain. Levodopa crosses the blood-brain barrier by way of the large neutral amino acid carrier transport system.
Levodopa is used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease. Levodopa is also used to treat these same muscular conditions when they are caused by drugs such as chlorpromazine (Thorazine), fluphenazine (Prolixin), perphenazine (Trilafon), and others.


Related Keywords: parkinson , medications , drug , parkinson's disease


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